Next-generation sequencing (NGS) has revolutionized the field of microbiology and has led to the identification of many previously unknown bacterial species. One of the areas where NGS has had a significant impact is in the analysis of bacteria in house dust. NGS allows for the rapid and accurate identification of all bacterial species present in a sample, including those that are difficult or impossible to culture using traditional methods. This has several important benefits for understanding the microbiome of house dust and its potential impact on human health.
Firstly, using NGS to identify bacteria in house dust allows for a more comprehensive understanding of the microbial diversity in these environments. Traditional culturing methods are limited by their inability to culture certain bacterial species, which can lead to a skewed representation of the microbiome. NGS overcomes this limitation by analysing the DNA of bacterial species present in a sample, regardless of their ability to be cultured. This enables researchers to identify bacterial species previously missed and, thus gain a more accurate understanding of the microbial ecology of house dust.
Secondly, using NGS to identify bacteria in house dust can help discover the potential health effects associated with exposure to these environments. There is growing evidence that the composition of the ecobiome in house dust can have significant implications for human health. For example, exposure to certain bacterial species in house dust has been linked to the development of CIRS, allergies, asthma, and other respiratory conditions. NGS can identify these potentially harmful bacterial species and we gain a better understanding of their distribution and prevalence in different environments.
Finally, using NGS to identify bacteria in house dust has important implications for developing strategies to mitigate the potential health risks associated with exposure to these environments. By identifying the bacterial species most commonly found in house dust and associated with adverse health effects, researchers can develop targeted interventions to reduce exposure to these bacteria. For example, this may involve the development of specialized cleaning products or the implementation of environmental control measures to reduce the prevalence of these bacterial species in indoor environments.